5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE

Product Name: 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
CAS No.: 145915-60-2
Chemical Name: 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
Synonyms: DAPH-7;DAPH 2;CGP 53353;CGP-53353 solid;5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione;PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem;5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE;5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE;1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]-;5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2
CBNumber: CB2299648
Molecular Formula: C20H13F2N3O2
Formula Weight: 365.33
MOL File: 145915-60-2.mol

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5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Property

storage temp.: 2-8°C
solubility: DMSO: >10mg/mL
form: solid
color: orange

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 539652
Product name: CGP-53353
Purity: The PKC
Packaging: 2mg
Price: $272
Updated: 2024/03/01

Sigma-Aldrich

Product number: C7866
Product name: CGP-53353
Purity: solid
Packaging: 5mg
Price: $313
Updated: 2022/05/15

Tocris

Product number: 2442
Product name: CGP53353
Purity: ≥99%(HPLC)
Packaging: 10
Price: $265
Updated: 2021/12/16

TRC

Product number: C583575
Product name: CGP53353
Packaging: 2.5mg
Price: $325
Updated: 2021/12/16

Usbiological

Product number: 254940
Product name: CGP 53353
Packaging: 10mg
Price: $531
Updated: 2021/12/16

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5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Chemical Properties,Usage,Production

Uses

CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines.

Definition

ChEBI: 5,6-bis(4-fluoroanilino)isoindole-1,3-dione is a member of phthalimides.

Biological Activity

Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro .

storage

Store at RT

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Suppliers

China 16 Europe 1 Germany 3 Switzerland 1 United Kingdom 2 United States 8 Global 31

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
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Aladdin Scientific

Tel: +1-833-552-7181
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BOC Sciences

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Email: info@bocsci.com
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ProdList: 9926
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145915-60-2, 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONERelated Search:

4-FLUORODIPHENYLAMINE 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE 4,5-DIANILINOPHTHALIMIDE 3,4-Dimethyldiphenylamine

CGP 53353

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE

5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE

5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2

DAPH 2

DAPH-7

PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]-

CGP-53353 solid

5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione

145915-60-2

C20H13F2N3O2

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Protein Kinase C (PKC)

Kinase/Phosphatase Biology

Serine/Threonine Kinase Inhibitors

Protein Kinase